EXTERACELLULAR L-ASPARAGINASE FROM LOCAL SOIL BACTERIA: PRODUCTION AND OPTIMIZATION OF PHYSIOLOGICAL CONDITION

Orabi, Hanaa M. and El-Fakrany, Esmail M. and Khalek, Eman S. Abdel and El-Kasaby, Aziza M. and Sidkey, Nagwa M. (2018) EXTERACELLULAR L-ASPARAGINASE FROM LOCAL SOIL BACTERIA: PRODUCTION AND OPTIMIZATION OF PHYSIOLOGICAL CONDITION. Al-Azhar Bulletin of Science, 29 (2). pp. 1-7. ISSN 1110-2535

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Official URL: https://doi.org/10.21608/absb.2018.33806

Abstract

L-asparaginase produced by Bacillushalotolerans OHEM18 finds broad applications due to its hydrolysis activity so used as therapeutic agents in combination with additional medications in the cure of acute lymphoblastic leukemia and also in food processing. In the present study, L-asparaginase production was optimizedand the optimum factors for production under submerged fermentation (SMF) of the asparaginase were pH 7.0 after 28h using glucose and asparagine as carbon and nitrogen sources, respectively while bagasse was the best inducer for L-asparaginase production under SSF.

Item Type:	Article
Subjects:	Archive Science > Medical Science
Depositing User:	Managing Editor
Date Deposited:	04 Sep 2024 04:35
Last Modified:	11 Sep 2025 03:40
URI:	http://catalog.journals4promo.com/id/eprint/1425

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