Ameliorative Effect of Cannabidiol against Gastric Ulcer Induced by Diclofenac in Rats

Purpose: The aim of his study is to examine the effect of using cannabidiol upon gastric ulcer induced by diclofenac in rats. Method: The experiment was conducted on four groups, with normal rats serving as a control in group one. A single oral dose of diclofenac was administered to Group 2 rats in order to induce a stomach ulcer. The rats in the third group were given a single oral dosage of diclofenac sodium, followed by a 5-day therapy with cannabidiol, which began three days before the diclofenac administration. Drug control on cannabidiol-treated rats in the final group (Group 4). Results: The investigation showed that when cannabidiol was administered, the levels of acidity from diclofenac use decreased, significantly. Conclusion: The investigation resulted in a decrease in overall acidity levels among the rats treated with diclofenac, indicating that cannabidiol was effective in treating the condition.